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Woman smiling - Obesity Clinical Research Study

Have you tried losing weight without success?


Obesity and excess weight (overweight) are common health conditions. They are caused when the body takes in more calories than it burns off, leading to weight gain. When left untreated, the extra weight can cause complications like diabetes, heart disease, high blood pressure, high cholesterol, obstructive sleep apnea, and other health issues. Although there are approved medications and procedures to treat obesity, these may not work for everyone or they may have unpleasant side effects. What we learn from the MOMENTUM study may help researchers learn more about a potential new option for people with obesity and excess weight.

Looking for options, but not sure where to start?
The purpose of this study is to measure the effects of the study medication on body weight in people with obesity or excess weight. Researchers will also look at the effects of the study medication on blood pressure, lipids (cholesterol and fat), and levels of glucose and insulin.

Who can join the study?
If you have tried to lose weight in the past without success, you may be able to join the study. Other study requirements include (but are not limited to) the following:

  • Between the ages of 18 and 75
  • Do not have type 1 or type 2 diabetes
  • Willing to follow diet and exercise counseling throughout the study

18 and 75

Study Topics


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Obesity Resources

  • The US obesity prevalence was 42.4% in 2017 – 2018.
  • From 1999 –2000 through 2017 –2018, US obesity prevalence increased from 30.5% to 42.4%. During the same time, the prevalence of severe obesity increased from 4.7% to 9.2%.
  • Obesity-related conditions include heart disease, stroke, type 2 diabetes, and certain types of cancer. These are among the leading causes of preventable, premature death.
  • The estimated annual medical cost of l icon in the United States was $147 billion in 2008. Medical costs for people who had obesity was $1,429 higher than medical costs for people with a healthy weight.

What is the study medication of the MOMENTUM study?

The study medication is designed to act like 2 hormones that are naturally produced by the body and are involved in regulating appetite, metabolism, and blood sugar. By working in the same way as these 2 hormones, the study medication may help people lose weight by decreasing appetite and increasing the amount of energy the body uses (metabolism).

Study participants will receive at no cost:

  • Diet and exercise counseling
  • Study-related lab tests and health assessments
  • Study support and monitoring by a healthcare team
  • The opportunity to help advance research around obesity and excess weight
  • Possible access to the study medication

This research study is enrolling people who:

Are you between the ages of 18 and 75?

Do not have type 1 or type 2 diabetes

Willing to follow diet and exercise counseling throughout the study

Do You Not Meet the Criteria for This Study?

You could still participate in other studies. Contact us to be added to our database and you’ll be notified about our future studies that may be right for you.